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更新于 9月3日

體內(nèi)動(dòng)物實(shí)驗(yàn)員(糖尿病/Contractor)

1.5-2.5萬(wàn)·13薪
  • 上海浦東新區(qū)
  • 1-3年
  • 碩士
  • 全職
  • 招1人

職位描述

大小鼠實(shí)驗(yàn)糖尿病肥胖動(dòng)物模型構(gòu)建原代細(xì)胞WB免疫染色脂肪細(xì)胞模型骨骼肌肉模型
    • 公司:外資藥企 
    • 職位:體內(nèi)實(shí)驗(yàn)員Research Associate
      (Obesity & Muscle Biology)
    • 地點(diǎn):浦東新區(qū)張江
    • 長(zhǎng)期/Contractor
    工作內(nèi)容:


    您將利用您的科學(xué)專(zhuān)業(yè)知識(shí)開(kāi)發(fā)和實(shí)施細(xì)胞檢測(cè)和離體/體內(nèi)模型,直接支持我們藥物發(fā)現(xiàn)項(xiàng)目的進(jìn)展


    1. Assay
    Development: Design, develop, and optimize a range of in vitro, ex vivo, and
    in vivo assays to test and validate potential therapeutic interventions 檢測(cè)開(kāi)發(fā):設(shè)計(jì)、開(kāi)發(fā)和優(yōu)化一系列體外、離體和體內(nèi)檢測(cè),以測(cè)試和驗(yàn)證潛在的治療干預(yù)措施;


    2. Hands-On
    Research: Apply your expertise in complex laboratory techniques, including: 實(shí)踐研究:運(yùn)用您在復(fù)雜實(shí)驗(yàn)室技術(shù)方面的專(zhuān)業(yè)知識(shí),包括:


    o Cell
    Culture: Isolate, culture, and analyze primary human or animal skeletal muscle
    cells and adipocytes 細(xì)胞培養(yǎng):分離、培養(yǎng)和分析原代人或動(dòng)物骨骼肌細(xì)胞和脂肪細(xì)胞;


    o Cell-Based
    Assays: Execute phenotypic and mechanistic assays focused on myoblast and
    adipocyte differentiation, glucose uptake, lipolysis, and fatty acid oxidation
    基于細(xì)胞的檢測(cè):執(zhí)行表型和機(jī)制檢測(cè),重點(diǎn)關(guān)注成肌細(xì)胞和脂肪細(xì)胞分化、葡萄糖攝取、脂肪分解和脂肪酸氧化;


    3. Molecular
    Biology: Perform RNA isolation and analysis, Western blots, and immunostaining
    分子生物學(xué):進(jìn)行RNA分離和分析、蛋白質(zhì)印跡和免疫染色;


    4. In
    vivo Assays: Perform animal studies involving compound administration,
    analysis of body composition, glucose tolerance test and blood sampling and
    tissue harvesting 體內(nèi)試驗(yàn):進(jìn)行動(dòng)物研究,包括化合物給藥、身體成分分析、葡萄糖耐量試驗(yàn)、血液取樣和組織采集;


    5. Data
    Analysis: Analyze and interpret complex experimental data to deepen our
    understanding of disease pathways and therapeutic responses 數(shù)據(jù)分析:分析和解釋復(fù)雜的實(shí)驗(yàn)數(shù)據(jù),以加深我們對(duì)疾病途徑和治療反應(yīng)的理解;


    6. Collaboration:
    Work closely with cross-functional teams to advance drug discovery projects
    focused on obesity and skeletal muscle diseases 合作:與跨職能團(tuán)隊(duì)密切合作,推進(jìn)以肥胖和骨骼肌疾病為重點(diǎn)的藥物發(fā)現(xiàn)項(xiàng)目;


    7. Innovation
    & Strategy: Stay current with the latest scientific literature and
    emerging technologies in adipose and muscle biology, integrating new knowledge
    into our research strategies 創(chuàng)新與戰(zhàn)略:了解脂肪和肌肉生物學(xué)的最新科學(xué)文獻(xiàn)和新興技術(shù),將新知識(shí)融入我們的研究戰(zhàn)略;


    8. Communication:
    Clearly and precisely present your findings to internal teams, key
    stakeholders, and governance committees 溝通:清晰準(zhǔn)確地向內(nèi)部團(tuán)隊(duì)、關(guān)鍵利益相關(guān)者和治理委員會(huì)介紹你的發(fā)現(xiàn);


    9. Compliance
    & Record-Keeping: Maintain meticulous and accurate laboratory records,
    ensuring full compliance with data integrity standards, safety protocols, and
    ethical guidelines 合規(guī)和記錄保存:保持細(xì)致準(zhǔn)確的實(shí)驗(yàn)室記錄,確保完全符合數(shù)據(jù)完整性標(biāo)準(zhǔn)、安全協(xié)議和道德準(zhǔn)則。





    候選人要求:


    1. A
    Ph.D. or M.S. in Cell Biology, Molecular Biology, Biochemistry, or a related
    field 細(xì)胞生物學(xué)、分子生物學(xué)、生物化學(xué)或相關(guān)領(lǐng)域的博士或碩士學(xué)位;


    2. A
    minimum of 3 years of hands-on laboratory research experience (for M.S.
    candidates) 至少3年的實(shí)驗(yàn)室實(shí)踐研究經(jīng)驗(yàn)(碩士生);


    3. Strong
    technical proficiency in cell culture (especially primary human/animal cells),
    cell-based assays, and molecular biology techniques (e.g., RNA analysis,
    Western blot) 對(duì)細(xì)胞培養(yǎng)(尤其是原代人/動(dòng)物細(xì)胞)、基于細(xì)胞的檢測(cè)和分子生物學(xué)技術(shù)(如RNA分析、蛋白質(zhì)印跡)有很強(qiáng)的技術(shù)熟練度;


    4. Minimum
    of one year’s experience with animal handling 至少一年動(dòng)物處理經(jīng)驗(yàn);


    5. Expertise
    in in vitro pharmacology using relevant cell types like adipocytes and
    skeletal/cardiac myocytes 使用脂肪細(xì)胞和骨骼/心肌細(xì)胞等相關(guān)細(xì)胞類(lèi)型的體外藥理學(xué)專(zhuān)業(yè)知識(shí);


    6. Experience
    with rodent diabetes and/or obese models 有嚙齒動(dòng)物糖尿病和/或肥胖模型的經(jīng)驗(yàn)


    7. Excellent
    communicator with strong written and verbal skills, capable of presenting
    complex scientific data to diverse audiences
    優(yōu)秀的溝通者,具有較強(qiáng)的書(shū)面和口頭表達(dá)能力,能夠向不同的受眾呈現(xiàn)復(fù)雜的科學(xué)數(shù)據(jù);


    8. Highly
    organized with a proven ability to prioritize multiple projects and meet
    deadlines without sacrificing quality or attention to detail
    組織能力強(qiáng),有能力優(yōu)先處理多個(gè)項(xiàng)目,并在不犧牲質(zhì)量或注重細(xì)節(jié)的情況下按時(shí)完成;


    9. A
    collaborative team player who fosters a culture of innovation, inclusion, and
    continuous learning 具有團(tuán)隊(duì)合作精神,培養(yǎng)創(chuàng)新、包容和持續(xù)學(xué)習(xí)的文化。

工作地點(diǎn)

浦東新區(qū)上海羅氏制藥有限公司

入職公司信息

  • 入職公司: 某大型公司
  • 公司地址: 上海靜安區(qū)
  • 公司人數(shù): 100-299人

認(rèn)證資質(zhì)

  • 人力資源服務(wù)許可認(rèn)證

    人力資源服務(wù)許可證是由國(guó)家人力資源與社會(huì)保障相關(guān)部門(mén)頒發(fā),代表人才經(jīng)紀(jì)人所在企業(yè)可以合法開(kāi)展人力資源相關(guān)業(yè)務(wù)的資質(zhì)證件。展示該標(biāo)簽代表該企業(yè)發(fā)布此職位時(shí)已上傳《人力資源服務(wù)許可證》或《人力資源服務(wù)備案證書(shū)》并經(jīng)由平臺(tái)審驗(yàn)通過(guò)。

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胡女士/招聘

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